This tutorial is a step-by-step guide for searching for motifs for the SET domain, which I have taught for epigenetics students.
“For example, a protein called Clr4 from S. pombe contains the SET domain. How could you find mammalian homologous of Clr4? Let’s assume that you find 8 proteins in human database containing SET domain. How close are they? Can we draw a tree out of it? Can we align all these protein sequences together and compare their similarity, and find the most conserved motif (like GXGNA) shared with all these proteins? If I would like to know where this motif located in 3D structure, can we look at it on the published protein structure database?”
During the recent change in federal government, researchers and librarians were concerned about loss of access to federal data, particularly in the area of environmental science where the new administration’s policies appeared to contradict scientific consensus. Early indications suggested that federal datasets and scientific information would be removed from the web entirely, or at least restricted in access.
In response to these concerns, a number academic institutions and other organizations began to organize data preservation efforts to ensure continued public access to endangered datasets. While websites of specific federal agencies continue to serve as the primary repositories of public data, this post focuses on a few public websites that aggregate and preserve federal datasets and provides a brief description of each.Continue reading →
Academic institutions are searching for ways to alleviate the financial burden that the increasing cost of textbooks places on their students. The average student spends $1200 annually for books and supplies, according to the Open Textbook Network. Science textbooks are especially expensive, but OERs, or Open Educational Resources, are gaining acceptance as alternatives to traditional textbooks (Open Textbook Network, 2017).
A survey conducted by the Pew Research Center in the fall of 2016 reports that 80% of US adults with some college and 89% of US college graduate own a smartphone. (Pew Research Center, January 11, 2017). Not surprising as the smartphone is the go-to for recent news, connecting with friends and family, and learning new things. We know that smartphones are popular with the college population but how are college students using them in support of their study, in particular engineering students?
MathSciNet is the premier index and reviews database for mathematics and related literature. It contains and continues from Mathematical Reviews (print), published from 1940 to 2012. Produced by the American Mathematical Society, MathSciNet is international in scope, covering over 1800 current journals with more than 3.3 million publications ranging from 1810 to the current day. Over 20,000 expert reviewers produce more than 80,000 reviews each year for MathSciNet. These add tremendous value to the more than 100,000 new citations added annually.
Most people are familiar with PubMed, BLAST, and other NCBI databases, but many may not know that it is possible to customize your searches in them. MyNCBI, a free account within PubMed and the other NCBI databases such as Genome and PubChem, facilitates many useful research tools. Here are a few ways you can use it to your advantage:
TRAIL, the Technical Report Archive and Image Library, is a project started by librarians 10 years ago to digitize technical reports produced by various agencies in the United States government and to make them available to all users.
In October, 2012, the U.S. Geological Survey (USGS) announced a new generation of the National Geologic Map Database, the index to United States maps. It has resulted from a partnership between the USGS and the AASG, the Association of American Geologists. Its antecedent directed searchers to regional map depositories, but now many maps and publications are freely available for downloading. Some maps must still be purchased or otherwise obtained.
MedlinePlus is a free health information resource from the United States’ National Library of Medicine. This post is not a comprehensive review of the entire site, but will give a general overview and highlight some of my favorite areas. MedlinePlus is geared to provide information for patients and the general public. Most of the information has been written at the 5th to 8th grade level. It is intended to be a consumer-based resource and not for medical professionals. The information within MedlinePlus provides selected links to reliable healthcare web sites and information generated at the National Library of Medicine. It contains links to over 975 medical topics, including links to the A.D.A.M. medical encyclopedia and the Merriam-Webster medical dictionary. The statistics page of the website reports that there is Information from over 1,000 organizations containing over 35,000 links to authoritative health information. Continue reading →
Nuclear energy is the energy contained in the nucleus of an atom. When the atoms are broken apart in the fission process, the energy released can be used to generate electricity. The most common element used in nuclear fission is uranium.
The U.S. Energy Information Administration (EIA) is a one-stop shop for all data and statistics on nuclear power. Topics covered include nuclear operable units, electricity generation, storage of radioactive waste, and state of operating nuclear power plants. While the focus of this data is on nuclear power in the United States, there is also data provided for yearly international nuclear electricity generation.